Symbol Name ID |
Adar
adenosine deaminase, RNA-specific MGI:1889575 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating antibody level |
Hematemesis |
Hematochezia |
Purpura |
Petechiae |
Pancytopenia |
Anemia |
Hemolytic anemia |
Lymphocytosis |
Chronic lymphatic leukemia |
Thrombocytopenia |
Neonatal alloimmune thrombocytopenia |
Splenomegaly |
Hepatosplenomegaly |
Disease(s) Associated with ADAR | ||||||||||||||
Aicardi-Goutieres syndrome |
Mouse Phenotypes | hematopoietic system phenotype |
abnormal embryonic erythropoiesis |
abnormal definitive hematopoiesis |
absent common myeloid progenitor cells |
impaired hematopoiesis |
decreased bone marrow cell number |
abnormal hematopoietic stem cell morphology |
abnormal spleen morphology |
|
Availability | Mouse Genotype | ||||||||
Adartm1.1Knk/Adartm1.1Knk | * | ||||||||
Adartm1Phs/Adartm1Phs | |||||||||
Adartm2Phs/Adartm2Phs | |||||||||
Adarem1Stsn/Adartm1Olds | |||||||||
Adartm2Knk/Adar+ | |||||||||
Adartm1Knk/Adartm1Knk Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
* | ||||||||
Adartm1.1Phs/Adartm2Phs Tg(Mx1-cre)1Cgn/? (conditional) |
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Adartm1.1Phs/Adartm2Phs Tg(Tal1-cre/ERT)42-056Jrg/? (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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