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Symbol
Name
ID
Adar
adenosine deaminase, RNA-specific
MGI:1889575
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating antibody level
Hematemesis
Hematochezia
Purpura
Petechiae
Pancytopenia
Anemia
Hemolytic anemia
Lymphocytosis
Chronic lymphatic leukemia
Thrombocytopenia
Neonatal alloimmune thrombocytopenia
Splenomegaly
Hepatosplenomegaly
Disease(s) Associated with ADAR
Aicardi-Goutieres syndrome

Mouse Phenotypes
hematopoietic system phenotype
abnormal embryonic erythropoiesis
abnormal definitive hematopoiesis
absent common myeloid progenitor cells
impaired hematopoiesis
decreased bone marrow cell number
abnormal hematopoietic stem cell morphology
abnormal spleen morphology
Availability Mouse Genotype
Adartm1.1Knk/Adartm1.1Knk *
Adartm1Phs/Adartm1Phs
Adartm2Phs/Adartm2Phs
Adarem1Stsn/Adartm1Olds
Adartm2Knk/Adar+
Adartm1Knk/Adartm1Knk
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+  (conditional)
*
Adartm1.1Phs/Adartm2Phs
Tg(Mx1-cre)1Cgn/?  (conditional)
Adartm1.1Phs/Adartm2Phs
Tg(Tal1-cre/ERT)42-056Jrg/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory